New SCIEX ZenoTOF 7600+ System Sets New Standard

At HUPO 2024, SCIEX introduced the ZenoTOF 7600+ system, the latest addition to its high-resolution accurate mass spectrometry line, designed to streamline protein biomarker research and accelerate proteomics breakthroughs. This innovative system brings SCIEX’s ZT Scan DIA method to researchers, merging the high depth of data-independent acquisition (DIA) with the accuracy of data-dependent acquisition (DDA) and targeted quantification techniques.

Key Features of the ZenoTOF 7600+ System

The ZenoTOF 7600+ is uniquely equipped with powerful features tailored to meet the demands of advanced proteomics:

• ZT Scan DIA Technology: Combines DDA, DIA, and targeted approaches within a single workflow, boosting protein group quantification by over 125% compared to standard methods.
• Electron Activated Dissociation (EAD): Provides tunable fragmentation for versatile molecular analysis.
• High-Speed Scanning: At 640 Hz, this is SCIEX’s fastest mass system, capable of supporting extensive quantitation panels.
• Enhanced MS/MS Data Accuracy: Uses Q1 quadrupole scanning to achieve precise isomeric peptide differentiation and PTM localization.

Collaborative Ecosystem for Comprehensive Proteomics

Complementing the ZenoTOF 7600+, SCIEX has partnered with three leading technology providers to support an integrated workflow for proteomics labs:

• PEAKS 12.5 from Bioinformatics Solutions Inc.
• Evosep One from Evosep
• Aurora Series XS Range from IonOpticks

By uniting these technologies, SCIEX’s expanded platform offers researchers a seamless, optimized solution for proteomics applications, empowering the field of precision medicine.