A Game-Changing Advantage in Biosafety Cabinet Monitoring
Are you looking for a solution to improve air monitoring to minimize contaminants in your lab?Does your lab suffer from the burden of costs and resources to maintain compliance?Biosafety Cabinets (BSCs) provide a clean,...
A Guide to Automated Sample Preparation Workflows: Thermo Scientific TriPlus RSH SMART
Gas chromatography is a separation technique widely used in
many analytical testing and research laboratories to unravel samples
composition or quantify impurities. It is a key analytical tool fo...
A new horizon for single-cell, quantitative, and translational proteomics
Looking to unlock additional insights into biology and disease mechanisms? With faster throughput, deeper coverage, higher sensitivity, and accurate and precise quantitation; the Thermo Scientific Orbitrap Astral Mass Spectro...
A Novel Approach to Capture Large, Variable Cells Using the Invitrogen Bigfoot Spectral Cell Sorter
Sorting very large cells with standard nozzle tip sizes on cell sorting flow cytometers can be challenging. This is primarily due to the scarce frequency of large cells and their fragile nature. The required pressures for 70,...
A Smarter Way to Scale with Automated Solvent Recovery
The Hei-VOLUME Distimatic Pro offers continuous, automated distillation without the need for constant operator intervention
Tired of bottlenecks from manual rotary evaporation? The Hei-VOLUME Distimatic Pro is ...
Absorbance and Fluorescence Quantification: An Application Guide to Sample QC
This essential guide explores complementary measurement
methods to address a range of quality control applications, ensuring reliable
data across diverse sample types.
Key Solutions ...
Understanding the
physiological state – or health – of your cells is the first step toward
experimental success during drug research. Cell stress, apoptosis, necrosis,
autophagy, and metabolic changes...
Breaking Barriers to Discovery with the Orbitrap Astral Mass Spectrometer
Since the launch of the Orbitrap Astral system at the 2023 ASMS conference, pivotal developments ranging from increased single-cell sensitivity and resolution to expanded quantitation and throughput have propelled the fields ...
Bridging the Gap from Biomarker Discovery to Verification
Stepping into the Thermo Fisher Scientific hospitality suite at the American Society for Mass Spectrometry (ASMS) annual conference was like being transported into the future. Beyond the three dimensions of space, time appe...
Challenges and Solutions in Multiplex Live Cell Imaging
Multiplex live cell imaging enables the observation of multiple cellular structures and processes simultaneously, offering a more physiologically relevant understanding of dynamic interactions. However, the approach presents ...
Correlating NGS Success with Sample Input Quality: A Large-Scale Study
The quality
of DNA samples is critical to the success of next-generation sequencing (NGS)
workflows. This study examines how using a DNA Integrity Number (DIN)- based
threshold can optimize sequencing by assessin...
In many CHO fed-batch approaches, the cell culture media, basal, and feed, are designed to supply enough nutrients for the majority of cell lines, but overfeeding may lead to the accumulation of toxic metabo...
Decoding the Data: A Guide to Cold Storage & Incubator Performance Metrics
In a lab environment where every degree matters, selecting the right refrigerator, freezer, or incubator can mean the difference between experimental success and costly setbacks. But how do you evaluate performance metrics that a...
Determination of Organic Carbon in Soil Samples: an Interlaboratory Study
The determination of organic carbon plays a fundamental role in the characterization of soils and sediments. Total organic carbon (TOC) analysis is indispensible in assessing soil health and fertility by indicating the ...
Emerging Analytical Solutions to the Challenges of PFAS Detection
PFAS contamination is a growing global problem with severe environmental and health implications. Regardless of the sources, measures must be taken to accurately detect and mitigate the buildup of PFAS chemicals in the en...
Emerging Analytical Solutions to the Challenges of PFAS Detection
PFAS contamination is a growing global problem with severe environmental and health implications. Regardless of the sources, measures must be taken to accurately detect and mitigate the buildup of PFAS chemicals in the enviro...
Spatial imaging is transforming how researchers understand biological complexity by visualizing the spatial distribution of biomolecules within tissue samples. To support scientists in extracting deeper insights from a si...
End-to-End Workflow Solutions for Short Nucleic Acids and mRNA Analysis
Short synthetic oligonucleotides, such as
small interfering RNA, antisense oligonucleotides, aptamers, and CRISPR guides
have gained much attention and grown rapidly as a new type of drug in gene
therapy. The suc...
Enhance Your Semiconductor Materials Characterization
The semiconductor industry is advancing at breakneck speed—pushing for faster, smaller, and more powerful devices. From 5G and AI to electric vehicles and advanced medical technologies, success depends on the precision ...
Enhanced Performance for Bioanalytical Labs with the SCIEX 7500+ System
Bioanalytical labs need reliable tools to deliver accurate results and meet tight drug discovery and development timelines. Downtime from less robust instruments can disrupt workflows, making durable and dependable systems es...
Pharmaceutical and biotech labs operating under FDA and EU
GMP requirements must meet stringent standards for electronic records and
electronic signatures. This white paper from Sartorius offers a comprehensive
c...
Essential Strategies for Laboratory Shaking Incubators
Laboratory shaking incubators are essential instruments for applications requiring precise temperature control and agitation, such as microbial growth, cell culture, and protein expression. However, their complex components&m...
Exploring Key Metabolic Differences in Manufactured CAR T-Cells
This study explores the relationship between CAR T-cell activation, nutrient metabolism, and treatment efficacy. It highlights differences in amino acid (AA) concentrations in spent media between potent CAR T-ce...
Water testing includes everything from routine drinking water screenings to targeted safety investigations following a Legionella outbreak. Regardless of the sample, water testing laboratories have the dual aim of obtaining r...
Protein purification
is an essential process in advancing protein science, disease research, and
therapeutic discovery. Filtering impurities and cell debris is critical for maintaining the accuracy and reproducibi...
Find Fast, Affordable Solutions for Your Elemental Analysis Needs
Different techniques used for elemental analysis can be
costly and time-intensive, challenging for labs and facilities operating within
budget constraints. If you’re seeking a more affordable, efficient way ...
The
growth in popularity and acceptance of Fourier transform infrared (FTIR)
spectrometers for use in quality assurance (QA) laboratories and on
manufacturing floors is one of the major developments affecting ind...
Going Green: Are Lab Water Impurities Compromising Your Research?
In our Going Green Whitepaper, discover six exciting research projects that are helping us to understand and reduce environmental water contaminants. We discuss the consequences of environmental water contaminants, including ...
This guide contains
step-by-step instructions for common imaging protocols, including tips for a
successful experiment, and lists of needed supplies.
Essential protocols
include:Cell proliferationCell viabili...
How Does Your Choice of Tube Affect Sample integrity?
What should I
consider when selecting tubes for cryopreservation?
How do I choose
the best tubes for automated liquid handling?
Is compatibility
a big concern when it comes to solvent-based samples?
...
Advancements in oligonucleotide therapeutics have created a need for innovative oligo synthesis workflow solutions. There are challenges that must be overcome to achieve the purity and quality control required for downstream ...
How to Use a “Total Workflow” Sample Prep Approach to Optimize Elemental Analysis
As atomic spectroscopy techniques for elemental analysis have advanced over the years, the need for better sample preparation has grown. While digestion is often the focal point, other steps in the sample preparation workflow can...
Biomolecular imaging tools, designed for the precise quantification of proteins, nucleic acids, and other biomolecules, play a critical role in all areas of life sciences. Imaging tools enable researchers to explore cellu...
Our goal is to support your immuno-oncology
research with a comprehensive range of tools and
technologies that maximize your time, budget, and
data—helping to accelerate your path to discovery
and translation to a c...
Improve Data Integrity Through Proper Lab Balance Cleaning
Achieving accurate weighing results relies heavily on maintaining clean laboratory balances, as contamination can compromise data integrity. Despite its importance, challenges persist including how to effectively address spil...
Innovations in Microwave Sample Preparation for Elemental Analysis
Microwave digestion has revolutionized sample preparation for elemental analysis and this eBook will uncover the...
Key Challenges
Labs
often face issues with digestion quality, operator safety, a...
Intuitive and Efficient FTIR Workflows for Improved QA/QC Analysis
FTIR
analysis has long been an integral part in quality assurance (QA) and quality
control (QC) in many industries, from pharmaceuticals, food & beverages,
and cosmetics to polymers and other chemicals. Typic...
Key Insights into the Function and Performance of Stability Chambers
Controlled environment testing is critical across industries where product stability, safety, and regulatory compliance are paramount. Stability chambers are precision- engineered units that maintain consistent temperature an...
Key Strategies for Compliant Sterility Testing in Pharmaceutical Labs
Sterility testing is a critical process to ensure that pharmaceuticals and medical devices remain free from viable contaminating microorganisms before release. This comprehensive guide addresses the challenges and provides step-b...
Did you know that in some cases, using fewer antibodies can result in more signal? Or, conversely, that using more antibody can result in less signal?A dot blot is a simplified version of a western blot that is performed to o...
Making the Jump to Faster, More Efficient HPLC Methods
Updating your older HPLC methods can help increase productivity, lower costs, and reduce your lab’s carbon footprint. Despite these advantages, there are concerns that you’ll lose performance and reliability i...
Mass Spectrometry, Large Biomolecules, and the Science of “More”
Mass spectrometry has a long and celebrated history as a foundational technique in biochemistry. Itsability to cleave molecules into charged fragments, then sort those fragments according to their mass-to-charge...
Whether you’re advancing microbiome studies, engineering microbial strains, or pioneering synthetic biology research, traditional colony picking workflows can be bottlenecks to success.• Multiple instruments and fr...
Laboratory balances are essential tools for applications ranging from pharmaceutical formulation to routine sample prep. However, achieving accurate, reproducible results is not always straightforward. Lab professionals often...
Meeting the Demands of Quality Control Labs with Ultra-High Resolution Balances
Quality control (QC) labs are at the forefront of ensuring product safety and efficacy, particularly in industries such as pharmaceuticals and biotechnology. These labs face mounting challenges, including stringent regulatory...
Mobile Phase Optimization for Synthetic Oligonucleotides
Analyzing synthetic oligonucleotides presents unique challenges due to their complex structures and modifications, such as phosphorothioate linkages and ribose alterations. These features can cause difficulties like band broa...
Monitoring Critical Bioprocess Parameters with MAVERICK
Monitoring and control of critical process parameters (CPPs) such as glucose and lactate are essential to maintaining optimal cell culture conditions, which includes ensuring product quality and maximizing yield...
On-Demand Webinar Event: Unlock GPCR Fragment Screening for Drug Discovery
GPCRs are notoriously difficult to study due to their intrinsic protein instability. By utilizing the sensitivity of Grating Coupled Interferometry (GCI) technology combined with non-clog microfluidics, these pesky membrane p...
Pharmaceutical development is a complex, resource intensive process that demands the latest technologies and solutions to provide the best chances at success.The discovery process requires high-quality...
Preparing for the Future with Sustainable Lab Balances
As lab managers increasingly prioritize sustainability and more ambitious targets are set, continued progress requires more multifaceted approaches. While many labs start by addressing concerns like energy consumption in cold...
Proper Pipetting and the Importance of Expert Training
How does your lab establish best practices for pipetting?
How can you ensure proper
training when onboarding new staff?
How can your lab stay
current with updates to regulations and compliance?
Pi...
Proper Pipetting and the Importance of Expert Training
How does your lab establish best practices for pipetting?How can you ensure proper training when onboarding new staff?How can your lab stay current with updates to regulations and compliance?Pipetting is a universal technique...
Reveal Hidden Details of CRISPR P53 Knockout Cells Using an Adapted Cell Painting Assay
Tumor protein p53 plays a pivotal role in regulating cell health—yet mutations in the p53 gene are implicated in nearly 50% of all cancers.
In this application note, researchers used the Therm...
Revolutionizing Drug Discovery: Challenges and Solutions in 3D Organoid Development
The development of three-dimensional (3D) organoids marks a pivotal advancement in drug discovery and biomedical research. These structures, capable of self-organizing and mimicking the functionality of human organ ce...
Revolutionizing iPSC Culture with Automation and AI
The CellXpress.ai Automated Cell Culture System is a groundbreaking solution for scaling up drug discovery and addressing the challenges of traditional induced pluripotent stem cell (iPSC) culturing. This innova...
Sanger Sequencing and Fragment Analysis applications
Get to know how capillary electrophoresis enables a variety of applications for a broad range of research areas through Sanger sequencing and fragment analysis.Sanger sequencing, the gold standard of sequencing, provides...
Solving Lab Purchasing Challenges with NuAire’s QuickShip Program
Purchasing laboratory equipment often involves long lead times, stock shortages, and uncertainty, causing delays in critical projects. These challenges are particularly pressing when labs are under tight timelines for set up ...
Modern molecular techniques rely on
reliable quantities of DNA or RNA. Accurate quantitation of nucleic acids is
critical for applications including molecular cloning, next gen sequencing,
ligation, PCR, transfec...
“It’s important to consider what you
going to be doing with the instrument. Are you going to be using it for multiple
different applications, or is it just a targeted application that you're
looking f...
The Complete Guide to Purchasing a Rotary Evaporator
“There are many factors to consider when selecting the proper rotary evaporator. Details including temperature control, batch size, and throughput requirements will help determine the best system for your lab.” - ...
The Power of AI-Driven Automation in Cell Passaging and Expansion
Cell-based models are essential for drug development and
biological research. However, traditional tissue culture remains one of the
most labor-intensive and error-prone aspects of laboratory work. Complex
protoc...
The Solution for Superior Data Integrity and Lab Compliance
The Thermo Scientific™ NanoDrop™ Eight Spectrophotometer builds on the NanoDrop 8000 - the original high-throughput NanoDrop instrument - and our flagship NanoDrop One/OneC Microvolume UV-Vis Spectropho...
For over four decades, microplate readers have been indispensable in scientific research, driving advances in protein and cell biology. When researchers choose a microplate reader, they are investing in technology d...
The Value of Certified Refurbished Analytical Instruments
During drug and biotherapeutic development, the ability
to measure binding activities between biomolecules is often critical. Such
interaction assays serve an important role in screening, antibody structure
analy...
Thermo Scientific™ TriPlus™ RSH SMART VOC Sample Prep Station
The Thermo Scientific™ TriPlus™ RSH SMART VOC Sample Prep Station in the dedicated dual-head configuration is a robotic autosampler for automating calibration standards preparation ...
Top 10 Tips for Blood Separation in Point-of-Care Tests
Effective blood separation is crucial for accurate point-of-care diagnostic testing using whole blood. However, the complexity of blood—comprising red and white blood cells, platelets, and plasma—poses challenges ...
Transform Your Lab with Innovative Bioreactors and High-Efficiency Flasks
Mammalian cell culture for cell line
development is a cornerstone of biomedical research and therapeutic production.
However, this process presents significant challenges, including the need for
stringent control...
Trusting the Source: Advantages of Purchasing Equipment Direct from the Manufacturer
Ensuring your equipment investment aligns with your lab’s long-term success
Purchasing lab equipment is a critical investment, and choosing the right source is key to ensuring quality, reliability, an...
Unlock Precision: Improve Single-Cell Counting with Countess™ 3 FL
Single-cell RNA sequencing (scRNA-Seq) and single-cell ATAC sequencing (scATAC-Seq) rely on precise single-cell counts to generate high-quality data. However, accurate enumeration is challenging due to the presence of cellula...
Unlock the Future of Cancer Treatment with Our Comprehensive Immuno-oncology Product Resource Guide
Immuno-oncology represents a transformative approach to cancer treatment, harnessing the power of the immune system to fight cancer. Our Immuno-oncology Product Resource Guide is your essential companion in this rapidly evolv...
Making the choice to replace or upgrade your mass spectrometer is an important decision. With multiple options available for buying new or pre-owned instruments, it’s important to know what to consider when ev...
Weighing the Essentials of Lab Balances: A Buyer’s Guide
Choosing the right lab balance is more than a purchase—it’s an investment in accuracy, efficiency, and long-term success.
“There are many factors which come into play considering buying a balance. Sta...