Driving the Field of Oligonucleotide Therapeutics: eBook

The research and development of oligonucleotides represents a revolutionary approach to discovering new and important therapeutic agents. There are challenges, however, in the synthesis, purification, and large-scale production of oligonucleotides. These challenges must be overcome to realize their true therapeutic potential.

Analytical testing solutions are essential in driving research to confidently identify and validate new therapeutic candidates. These analytical solutions include raw/starting material analysis for oligonucleotide synthesis, purity analysis, sequence confirmation, and purification techniques to support validation and quality control for downstream applications. Preparative solutions are necessary to enable oligonucleotide production and scale-up to manufacturing.

This eBook highlights the associated complexities of oligonucleotide synthesis and the range of technologies designed to streamline and advance oligonucleotide characterization, purification, and scale-up to production.