The Alkalizator is a state-of-the-art automated in-line lysis system designed to streamline microbial downstream processing. Engineered for plasmid DNA and recombinant protein production, this innovative solution enhances control, efficiency, and impurity reduction in laboratory workflows.

Key Features of Alkalizator

• Closed single-use flowpath for contamination-free operation
• Processes up to 500 L/day of resuspended cells, with a 2000 L scale-up version coming soon
• Advanced mixing control for precise lysis and neutralization
• Scale-down mode available for screening as low as 0.1 L per run
• Single-use and cGMP compliant, with a multi-use option available
• No chilled reagents required, reducing operational costs

Transforming Process Development

The Alkalizator integrates advanced automation and real-time control to improve productivity while ensuring high-quality plasmid DNA isolation. By eliminating the need for chilled reagents and enabling efficient separation of debris from lysate, the system reduces contaminant levels and enhances process reliability.

This scalable solution supports laboratories and manufacturers aiming to optimize alkaline lysis workflows while reducing production costs.