How Pure is Your Oligo?

Instruments and solutions for oligonucleotide synthesis and purity analysis

Advancements in oligonucleotide therapeutics have created a need for innovative oligo synthesis workflow solutions. There are challenges that must be overcome to achieve the purity and quality control required for downstream applications and scale-up to manufacturing.

Purity analysis identifies closely related failed sequences and other impurities in order to optimize yields.

Target plus impurities analysis focuses on high-resolution accurate mass characterization of target oligos and low abundance impurities to monitor the quality, stability, and efficacy of synthesized oligos.

This infographic highlights the instruments and technologies designed to streamline these workflows by optimizing sample preparation, separation, detection, and oligo analysis.

Whether you’re performing purity analysis or target plus impurity analysis, Agilent has everything you need for each step of the process.

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